What event is known as the largest single land run in American history?

The Land Run of 1889 is recognized as the largest single land run in American history because it marked the opening of the Unassigned Lands in Oklahoma Territory for settlement. On April 22, 1889, thousands of settlers, known as "sooners," raced to claim parcelled land that had previously been designated for Native American tribes. This event symbolized the westward expansion of the United States and the aggressive push for settlement in the newly available territories, drawing immense public attention and facilitating a significant influx of settlers.

The Land Run set the precedent for future land runs, including those in 1893, 1901, and 1910, but the 1889 event was distinguished not only by the sheer number of participants but also by its dramatic, spontaneous nature. The vast expanse of land opened for claim during this run was over two million acres, which further solidifies its status as the largest land run in history.